Postdoctoral Researcher in Scientific Machine Learning and Computational Biology

The Maddu Lab in the Department of Applied Mathematics and Statistics and Data Science and AI Institute (DSAI) at Johns Hopkins University (JHU) is seeking a highly motivated postdoctoral researcher interested in developing theoretical frameworks and computational methods at the interface of scientific machine learning, biophysics, and computational biology.

The Maddu Lab integrates first-principles biophysical modeling with modern ML/AI techniques to build predictive, mechanistic models of complex biological processes from sparse, noisy, and high-dimensional data. Complementarily, we use concepts from statistical physics and dynamical systems theory to developtheoretical frameworks for understanding the behavior and learning dynamics of large AI models, with an emphasis on interpretability, robustness, and generalization.

The Maddu Lab emphasizes the judicious development of theory- and physics-guided

ML/AI tools to enable scientific discovery in the life sciences and medicine.

The postdoctoral researcher will have substantial flexibility in shaping their research program, with potential projects including: (i) Biophysical and mathematical modeling of intracellular and intercellular processes; (ii) Learning spatiotemporal dynamical models from time-series and snapshot data; (iii) Theory of learning in physics-informed neural networks; (iv) Biophysically informed sequence-to-function models.

Candidates must hold a Ph.D. (or equivalent doctoral degree) in applied mathematics, statistics, physics, computer science, computational biology, or a related field by the start date. Strong mathematical and computational skills are desirable. Expertise in one or more of the following areas would be particularly relevant: scientific machine learning, biophysical modeling, statistical learning theory, generative modeling, computational biology, or bioinformatics.

(1) a CV, (2) a brief statement of research interests, and (3) contact information for 2-3 references. In the research statement, candidates are encouraged to describe which of the research directions above most closely aligns with their interests and to propose related questions they would be excited to pursue. Applications will be reviewed on a rolling basis until the position is filled.

Salary Range

The referenced salary range represents the minimum and maximum salaries for this position and is based on Johns Hopkins University's good faith belief at the time of posting. Not all candidates will be eligible for the upper end of the salary range. The actual compensation offered to the selected candidate may vary and will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, internal equity, market conditions, education/training and other factors, as reasonably determined by the University.

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Pre-Employment Information

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Background Checks

After receiving a conditional offer, the successful candidate(s) for this position will be subject to a pre-employment background check including education verification. When deciding whether a candidate's conviction history is job-disqualifying, the University considers the nature and gravity of the offense, the time that has passed since the conviction, and the nature of the job being sought.

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Vaccine Requirements

Johns Hopkins University requires all faculty, staff, and students to receive the seasonal flu vaccine. Exceptions to the flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. New hires with start dates after the required vaccination deadline and during the designated flu season must be fully vaccinated before their start date to begin working.

For positions in clinical areas or laboratories, or for those that involve work with research subjects or community contact, the pre-employment physical requires a TB screening at least six weeks before your start date. TB screening can be a negative PPD test or an IGRA (T-spot or Quantiferon blood test). A chest X-ray may be required if your TB screening is positive. Documentation of immune status against rubella (German measles), rubeola (measles), mumps, varicella (chickenpox), and hepatitis B, and documentation of having received the Tdap (tetanus, diphtheria, and pertussis) vaccination is required. This may include documentation of having two (2) MMR vaccines, two (2) varicella vaccines, or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers.

Any vaccinations required for these diseases will be given at no cost in our Occupational Health office. An applicant who chooses to have his or her own practitioner complete the above requirements is responsible for those incurred costs.