Postdoctoral Research Associate, Neurometabolic Mechanisms of Cognitive Decline

The Cognitive Aging and Neural Dynamics Lab at the University of Arizona is seeking a Postdoctoral Research Associate to investigate how hypothalamic glucose signaling and molecular changes contribute to cognitive decline during aging and risk for Alzheimer's disease. The researcher will combine proteomics with fiber photometry measurements of glucose levels in the hypothalamus, integrating these data with measures of cognition and disease risk. This mentored research appointment offers opportunities to develop an independent research direction, publish findings, present at scientific meetings, and pursue fellowship or grant funding.

The Department of Neuroscience at the University of Arizona advances education and research across the diverse and interdisciplinary field of neuroscience. Our work spans a broad range of areas, including nervous system development and physiology, behavior, genetics, pharmacology, computational modeling, and neurological and psychiatric disorders. Through innovative education and research, the department is committed to advancing understanding of the nervous system and preparing students and scholars to contribute to this dynamic and rapidly evolving field of modern science.

Outstanding U of A benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; U of A/ASU/NAU tuition reduction for the employee and qualified family members; access to U of A recreation and cultural activities; and more!

The University of Arizona has been recognized for our innovative work-life programs. For more information about working at the University of Arizona and relocations services, please click here.

• Design
  and conduct studies of hypothalamic glucose dynamics using fiber
  photometry.
• Develop
  and carry out proteomics experiments, including sample preparation,
  quality control, and analysis in collaboration with relevant research
  facilities.
• Integrate
  molecular, physiological, and cognitive data to test hypotheses about
  aging and Alzheimer's disease risk.
• Maintain
  accurate research records; analyze and interpret results; and prepare
  manuscripts, presentations, and funding applications.
• Collaborate
  with laboratory members and research partners, and mentor trainees as
  appropriate.
• Complete
  required research, animal-use, and laboratory-safety training before
  undertaking applicable work.

• Ph.D. or
  equivalent doctoral degree in neuroscience, nutrition, biology,
  biochemistry, physiology, or a closely related field by the start date.
• Demonstrated
  experience designing and conducting research and analyzing experimental
  data.
• Evidence
  of scientific communication through publications, presentations, or a
  doctoral research project.

• Experience with mass-spectrometry-based proteomics or related protein-analysis workflows.
• Experience with fiber photometry, optical biosensors, or in vivo physiological measurements.
• Experience studying metabolism, hypothalamic circuits, cognitive aging, or Alzheimer's disease in rat models.
• Experience with quantitative analysis that integrates multiple types of biological data.