Research Technician III

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A Brief Overview
This role participates in planned research projects by performing research protocols with minimal direction and guidance from the principal investigator, program director or senior scientists. May exercise moderate discretion and judgment in the execution and interpretation of experiments, and of data derived.

Dr Tasian's translational laboratory in the Division of Oncology and Center for Childhood Cancer Research focuses upon the development of new treatments for high-risk childhood leukemias with an emphasis upon small molecule inhibitor therapies and cellular (CAR T cell) immunotherapies. Dr Tasian is seeking a motivated, dynamic, and hard-working Research Technician to join her laboratory to assist with preclinical animal model studies and with correlative biology studies for childhood leukemia clinical trials using primary patient samples.

What you will do

• Ability to process patient leukemia specimens following appropriate training, handle confidential patient-related materials, and maintain a protected database of confidential patient-related information from clinical trials.
• Ability to perform specialized animal studies (immunocompromised mice) for human leukemia xenotransplantation, preclinical drug or cell therapy treatment, disease monitoring, treatment efficacy analyses, and pharmacodynamic monitoring. Specific animal skills will be mastered after training and include retro-orbital venous bleeding, tail vein injections, intraperitoneal injections, oral gavage, bioluminescent imaging, and tissue processing.
• Ability to learn specialized flow cytometry analysis of mouse and human samples and to use flow cytometry data analysis and graphing software.
• Ability to troubleshoot and plan experiments with appropriate Principal Investigator and post-doctoral fellow oversight. Ideally, the candidate will contribute to writing of scientific manuscripts and to figure preparation; co-authorship will be commensurate with level of project involvement and manuscript contributions.
• Ability to handle multiple, time-dependent tasks efficiently and conscientiously and to conduct oneself with professionalism and maturity. Being a good team player is a must for our laboratory culture, and a good sense of humor is also quite welcome!
• Excellent organizational and analytical skills.
• Ability to use computers, email, Word, and PowerPoint software and to learn other programs needed for data presentation and figure preparation (eg, Prism).
• Performs research procedures on experimental samples with minimal supervision
• Formulates and performs complex lab experiments and analyzes/ reports the data
• Performs tasks that require knowledge of advanced techniques and lab equipment
• Performs advanced calculations and maintains appropriate log and lab notebooks
• Assists with planning specific research protocols and procedures
• Assists in development & troubleshooting of new techniques and ideas
• May be required to modify scientific methods and protocols (in conjunction with PI)
• Checks others' results for completeness and accuracy
• May be responsible for training and mentoring new staff
• May assist in the preparation of grants journal articles, posters and oral presentations
• May perform routine and non-routine tests / experiments as needed
• Maintains office, lab area, reagents, supplies and equipment
• Performs routine maintenance on lab equipment
• Coordinates schedules of tests & procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook in an organized manner
• Conducts literary searches as required

Education Qualifications

• High School Diploma / GED - Required
• Bachelor's Degree - Preferred

Experience Qualifications

• At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Required
• At least three (3) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Preferred

Skills and Abilities

• Advanced understanding of lab procedures, protocols, and equipment.
• Intermediate proficiency with lab specific experiments / techniques.
• Intermediate scientific analysis skills.
• Excellent verbal and written communications skills
• Excellent organizational skills
• Strong critical thinking / problem-solving skills
• Strong analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

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SALARY RANGE:

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.