Clinical Research Coordinator - Duke Cancer Institute

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute (DCI) is seeking a Clinical Research Coordinator (CRC) to join the Cancer Patient Experience Research Program (CPEP). In this dynamic and impactful role, you will lead and coordinate research studies focused on cancer patients' experiences and palliative care while also contributing to large-scale system implementation work through the electronic Patient Reported Outcomes (ePRO) PCORI Health System Implementation Initiative (HSII).

You will play a key role in advancing research that directly improves patient care and outcomes. Your day-to-day work will include supporting minimal-risk, mixed-methods research studies (quantitative, qualitative, and quality improvement), managing patient-facing research activities, and helping deploy innovative tools like Epic's eSym module across 45 cancer clinics. You'll work closely with patients, clinicians, and research teams-ensuring studies are compliant, data is accurate, and participants are supported throughout their research journey.

This is an excellent opportunity for someone who thrives in a collaborative, fast-paced research environment and wants to make a meaningful impact in oncology and patient-centered care research.

Minimum Requirements:

• Completion of an Associate's degree
• Minimum of two years of relevant clinical research experience. Completion of the DOCR North Carolina state-approved Clinical Research Apprenticeship program may substitute for one year of experience
• Experience supporting research protocols, including recruitment, consent, and data collection
• Ability to manage multiple competing priorities effectively
• Strong organizational, verbal, and written communication skills
• Ability to use computer software, web-based applications, and learn new systems
• Ability to work both independently and collaboratively with professionalism and respect

Preferred Qualifications:

• Bachelor's degree
• Experience with surveys and interviews in clinical research
• REDCap experience
• Familiarity with Patient Reported Outcomes (PROs) and patient outcomes research
• Experience with data capture forms and Electronic Data Capture (EDC) systems
• Experience in oncology, palliative care, or regulatory environments
• Experience with electronic medical records (EMR) and OnCore

Other Requirements:

• Basic Life Support (BLS) certification (American Heart Association or Duke-approved equivalent)
• Ability to support study compliance, regulatory documentation, and audit readiness
• May support training delivery, clinic onboarding, and workflow implementation across multiple sites

Be Bold.

Position Responsibilities:

• Coordinate and manage clinical research operations (55%)




• Develop and implement recruitment, screening, consent, and retention strategies
• Recruit, screen, and enroll study participants; conduct and document study visits
• Maintain study compliance with institutional policies and regulatory requirements
• Manage study documentation including regulatory binders, enrollment logs, and system records
• Record and report adverse events (AEs) and maintain Delegation of Authority logs
• Prepare and submit IRB documentation and support development of COI, DSMPs, and RDSPs
• Support study financial tracking, participant payments, and budget coordination
• Contribute to study start-up, closeout, and monitoring activities

• Support ePRO implementation and clinic engagement (HSII initiative)




• Assist with rollout of Epic eSym module across 45 cancer clinics
• Review and improve patient-facing educational and training materials
• Deliver training to clinic staff on workflows and ePRO utilization
• Conduct site procedural compliance audits and support ongoing quality improvement

• Manage and ensure quality of research data (25%)




• Utilize EMR and EDC systems to collect, manage, and validate data
• Develop and implement data collection tools, surveys, and questionnaires
• Ensure data accuracy, completeness, and security compliance
• Identify and resolve data discrepancies and suggest process improvements

• Facilitate communication and collaboration (10%)




• Serve as liaison between study teams, sponsors, investigators, and internal stakeholders
• Communicate study updates, escalate issues appropriately, and respond to inquiries promptly
• Support literature reviews and contribute to protocol development, presentations, and publications

• Provide leadership and mentorship (5%)




• Participate in team meetings, committees, and cross-functional initiatives
• Train and mentor team members on study processes and responsibilities
• Support professional development and actively engage in learning opportunities

• Ensure ethical conduct of research (5%)




• Adhere to all SOPs, regulations, and ethical guidelines governing clinical research
• Educate staff and participants on distinctions between clinical care and research
• Maintain required certifications and ensure compliance with institutional policies

Choose Duke.

Join Duke Cancer Institute's Cancer Patient Experience Research Program, where innovation, compassion, and discovery come together to improve the lives of cancer patients. You'll be part of a collaborative research environment focused on advancing patient-centered outcomes and implementing cutting-edge tools like ePROs at scale.

Duke University is consistently ranked among the top academic and research institutions globally, offering you the opportunity to contribute to meaningful, high-impact work alongside leading experts in oncology and palliative care.