Visiting Grad Student

Be You.

The Lan Lab is dedicated to researching how cancer cells respond to DNA damage through DNA repair mechanisms and developing innovative strategies to target these pathways in cancer therapy. Our significant contributions include uncovering the critical role of PARP in DNA repair, leading to successful applications of PARP inhibitors in the treatment of breast, ovarian, and other types of cancer. We study how DNA responds to oxidative damage at specific chromosomal locations, significantly advancing our understanding of DNA damage response in different chromosomal environments. Furthermore, our recent investigations have revealed a novel mRNA and R-loop-dependent DNA repair pathway that acts as a protective mechanism for the transcribed regions of the genome, introducing a new paradigm in the field of DNA repair research.

The incumbent will study function of immune activation in cancer treatment. They will use our established WT and knock out cell lines to exam immune activation and effects of different inhibitors in cancer therapy.

What we value:

Growth Mindset: A strong willingness to learn, adapt, and develop new skills. We value curiosity and a proactive approach to problem-solving.

Dedication and Efficiency: We seek individuals who thrive on doing experimental work, and who have a passion for repeatedly conducting detail-oriented experiments with a focus on precision and efficiency. We seek individuals who are self-motivated and dedicated to continuous improvement.

Communication Skills: Ability to communicate effectively within a team and contribute to a collaborative research environment.

Experience

Min Degree Requirements: BA or BS
Other Credential/Experiential Requirements: Student must be engaged in graduate research sponsored by a Duke faculty member.

This position is:

• Onsite. The work is performed on-site or at a designated assignment location.

Be Bold.

The research conducted by the Lan Lab strives to advance our understanding of DNA repair processes in cancer and the role of RNA and R-loops in these processes. We are dedicated to translating our findings into innovative therapeutic strategies that have the potential to revolutionize cancer treatment and improve patient outcomes.

ChooseDuke.

Be part of a dynamic team committed to innovating in the fields of genomics, nutrition, and public health. Our lab offers a stimulating environment where your contributions will have a meaningful impact on scientific research and public health. We welcome applicants who are passionate about advancing genomic technologies and are ready to embark on a challenging and rewarding research career.