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Research Lab Technician II - Microbiome

Massachusetts General Hospital
$24.28 - $39.43
United States, Massachusetts, Boston
185 Cambridge Street (Show on map)
Jun 05, 2026
Carries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit.
Does this position require Patient Care? No
Essential Functions
-Executes protocols of non-routine experiments.
-Assists PI with determining the most suitable methodology.
-Performs basic design and modification of protocols.
-Calculates, transcribes, and analyzes data.
-Prepares and presents reports.
-Organizes and summarizes acquired data using scientific and Statistical Techniques.
-Participates in the design of experiments or field work

Education
Bachelor's Degree Related Field of Study required

Can this role accept experience in lieu of a degree? Yes

Licenses and Credentials

Experience
Previous Research Lab Experience 1-2 years required

Knowledge, Skills and Abilities
- Analytical skills and ability to resolve technical problems.
- Ability to interpret acceptability of data results.
- Strong Computer skills.
- Demonstrated competence in research techniques and methodologies.

The Xavier Lab is seeking a Research Technician to contribute to studies of the gut microbiome and its role in human health and disease. Current projects investigate the ecological and functional properties of intestinal microbial communities, mechanisms governing host-microbe interactions, and the development of experimental approaches to understand how commensal bacteria influence inflammation, metabolism, and colonization resistance.

Recent work from the lab has linked gut microbial metabolism to cholesterol and cardiovascular disease risk in the Framingham Heart Study (PMID: 38569543), revealed how microbiota-driven immune responses shape intestinal biology (PMID: 39567686), and identified microbial communities that suppress pathogenic Enterobacteriaceae colonization (PMID: 39294375). These studies combine microbial cultivation, genomics, and host biology to understand mechanisms underlying human disease.

The ideal candidate will have a strong interest in hands-on microbiology and microbiome research, particularly the cultivation and characterization of anaerobic gut bacteria. The candidate should be self-motivated, detail-oriented, and capable of troubleshooting experimental challenges independently. This position provides training in microbiology, microbial ecology, anaerobic culturing, next-generation sequencing, and host-microbe interaction research. The successful candidate will have opportunities to contribute intellectually to projects, present findings at lab meetings, and participate in manuscript preparation.



The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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