Senior Research Associate - 140003

Established in 1978 at the UC San Diego Medical Center, the Department of Emergency Medicine (DEM) combines the benefits of an internationally renowned university with a large academic hospital. The UC San Diego Medical Center and the DEM is leading an effort, funded by the Federal Office of the National Coordinator, to foster data exchange, interoperability, and clinical integration to improve healthcare efficiency and patient outcomes among San Diego County community healthcare providers. The San Diego Beacon Collaborative will focus on expanding pre-hospital emergency field care and electronic information transmission to improve outcomes for cardiovascular and cerebrovascular disease, empowering patients to engage in their own health management through web portal and cellular telephone technology, improving continuity of care for all.

The Senior Research Associate will be responsible for advanced electron microscopic research and surgical procedures to produce animal stroke models in mice and rats. The incumbent performs electron and confocal microscopic imaging analysis, molecular and biochemical analysis such as Western blotting, ELISA assays, in situ hybridization, etc. This position also performs some research data analysis and creates graphs, writes positions (e.g., materials and methods) of manuscripts, and submits manuscripts for publications.

The program is highly interdisciplinary, utilizing animal surgery, cell culture, molecular and cellular biology, biochemistry, pharmacology, and quantitative histological analysis. Performs other duties as assigned.

• Knowledge of molecular and cellular biology, biochemistry, pharmacology, and/or quantitative histological analysis as typically attained by an advanced degree, or an equivalent combination of education and experience.

• Considerable experience with independent research/evaluation design and protocol development theory, methods, concepts, and techniques.

• Strong demonstrated ability to make and contribute important original ideas pertaining to the planning, development, modification, and execution of new research studies.

• Demonstrated leadership skills.

• Knowledge of statistical theory and methodology.

• Expert knowledge of methods and techniques of compiling, analyzing and evaluating statistical and other project/research data.

• Demonstrated ability to conduct independent scientific research and skills to organize and present such information at conferences and in scientific publications.

• Extensive experience in writing portions of scientific manuscripts applying knowledge and understanding of the science and research projects relating to interventions.

• Proven skill to communicate methods and results to provide interpretive information to scientific Investigators from which researchers can draw conclusions.

• Excellent oral and written communication skills.

• Skills and experience with performing animal stroke models, cell cultures, gene cloning and expression, Western blotting, confocal and electron microscopic analysis.

• Skills and extensive experience in performing animal stroke models and behavioral tests.

• Skills and extensive experience in advanced electron microscopy techniques, such as Serial Block-Face Electron Microscopy (SBEM) and Electron Tomography (ET).

• Skills and extensive experience performing confocal microscopy and quantitative histological analysis.

• Skills and experience in statistical/project/research data analysis.

• Job offer is contingent upon satisfactory clearance based on Background Check results.