We use cookies. Find out more about it here. By continuing to browse this site you are agreeing to our use of cookies.
#alert
Back to search results
New

Director, S2P COE - Strategy, Governance & Excellence

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
May 05, 2026

Job Description

The Director, S2P - Strategy, Governance & Excellence is a critical leadership role responsible for establishing the foundational operating model, governance, and standards for the SourcetoPay (S2P) Center of Excellence. This role serves as the architect, steward, and driver of procurement excellence, ensuring scalable processes, strong governance, digital enablement, and continuous capability advancement across the enterprise.

This leader will operate at the intersection of strategy, execution, and influence, partnering closely with Sourcing leadership, Finance, Legal, Sustainability, Digital/IT, and business stakeholders to elevate departments impact and maturity. The role directly supports enterprise value creation through supplier relationship management (SRM), small business engagement, supplier excellence, and capability building.

The Director will be accountable for Process Design & Optimization, Supplier Programs, and Capability & Change, and will play a visible role in shaping enterprisewide procurement transformation.

Key Responsibilities

1. Set the Foundation: Strategy, Governance & Operating Model

  • Be accountable for endtoend CoE outcomes, including progress against maturity goals, governance effectiveness, and value enablement.
  • Design and establish enterpriselevel governance frameworks, policies, and standards for Procurement and S2P activities.
  • Define and maintain the Procurement / S2P CoE operating model, including decision rights, controls, forums, and escalation mechanisms.
  • Serve as the custodian of procurement standards, ensuring consistency, compliance, and scalability across regions and business units.
  • Partner with Legal, Finance, Risk, and Compliance to ensure governance frameworks align with regulatory, contractual, and audit requirements.
  • Drive clarity in roles, accountabilities, and ways of working across the Procurement ecosystem.

2. Process Excellence & Optimization

  • Lead endtoend S2P process design, optimization, and standardization, grounded in leading practices and enterprise needs.
  • Apply a market and benchmarking lens to evaluate S2P maturity, inform standards, prioritize capability investments, and guide futurestate design decisions.
  • Establish a culture of continuous improvement, leveraging Lean, process excellence, and datadriven performance insights.
  • Define and track process performance metrics to monitor efficiency, effectiveness, and user experience.
  • Ensure process designs are digitally enabled, scalable, and aligned with futurestate technology roadmaps.

3. Enable External Value & Supplier Excellence

  • Advance Strategic Supplier Relationship Management (SRM) frameworks to deepen collaboration, innovation, and value realization with key suppliers.
  • Oversee supplier performance management, development programs, and continuous improvement initiatives.
  • Champion small business engagement strategies, including program design, governance, reporting, and stakeholder alignment.
  • Embed sustainability, ESG, and responsible sourcing considerations into supplier governance, performance, and development models.
  • Partner with category leaders and business stakeholders to move Procurement from transactional execution to strategic value creation.

4. Capability Building & Change Leadership

  • Design and execute a Procurement capabilitybuilding strategy, covering skills, behaviors, tools, and career pathways.
  • Develop structured learning, enablement, and knowledgesharing programs across the function.
  • Lead enterpriselevel change management efforts tied to process, technology, and operating model transformations.
  • Act as a thought leader and coach, raising the overall maturity and confidence of procurement professionals.
  • Reinforce a culture of innovation, accountability, and continuous learning.

5. Performance, Insight & Value Governance

  • Define the enterprise performance framework for Procurement and S2P, including value, risk, compliance, supplier performance, and maturity indicators.
  • Establish standards for KPIs, scorecards, and management insights required to enable effective governance, SRM, supplier excellence, and leadership decisionmaking.
  • Act as the business owner of "what must be measured and why," ensuring metrics align to strategy and external value objectives.
  • Partner with the S2P Process, Controls & Analytics Director on how insights are produced and governed, without owning operational reporting or analytics execution.
  • Partner with the User Orchestration, AI & Innovation Director to ensure insights influence behavior, adoption, and decision flow, without owning experience design or technology enablement.
  • Use performance insights to shape priorities, maturity roadmaps, capability investments, and continuous improvement agendas.

6. People Leadership & Stakeholder Influence

  • Lead and develop a team of three managers across:
    • Process Design & Excellence
    • Small Business Engagement
    • Capability Building & Change Management
  • Set clear objectives, empower leaders, and create strong crossfunctional collaboration.
  • Act as a trusted advisor to senior Procurement and enterprise leaders.
  • Represent the CoE in executive forums, SteerCos, and crossfunctional governance bodies.
  • Lead complex negotiations and influence outcomes across senior stakeholders, balancing competing priorities related to governance, risk, capability investment, and business impact.

Qualifications & Experience Required

  • 10+ years of progressive experience in strategic leadership roles within Procurement, S2P, Supply Chain, or adjacent functional domains.
  • Deep experience in governance frameworks, policy development, and process design within complex organizations.
  • Demonstrated expertise in Supplier Relationship Management (SRM), supplier performance, and external value creation.
  • Strong background in capability building, organizational change, and transformation leadership.
  • Proven ability to operate in highly visible, ambiguous, and matrixed environments.
  • High proficiency in digital enablement, data, metrics, and performance management.
  • Track record of building and leading highperforming teams.

Preferred

  • Experience establishing or scaling a Center of Excellence.
  • Familiarity with small business programs, diversity sourcing, or supplier sustainability initiatives.
  • Exposure to global or enterprisescale procurement transformations.

Leadership Attributes

  • Enterprise thinker with the ability to balance strategy and execution.
  • Strong influencer who can lead without authority.
  • Comfortable operating in complexity and driving clarity.
  • Credible, confident communicator at executive level.
  • Passionate about building foundations that enable longterm excellence and value.

Pay Range:

$180,000 - $270,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Applied = 0

(web-bd9584865-cxkl2)