New

AI Security Engineer

Duke Clinical Research Institute
United States, North Carolina, Durham
300 West Morgan Street (Show on map)
May 05, 2026
AI Security Engineer - IT Security Office (ITSO) Be You. Be Bold. Choose Duke. Be You. Introduction The Duke University Office of Information Technology (OIT) is seeking an AI Security Engineer to join the IT Security Office (ITSO). ITSO is responsible for coordinating, implementing, and assessing information security across Duke University. In this role, you will help design, deploy, and operate Duke's AI security architecture while working collaboratively with identity and access management teams, compliance officers, and AI developers across the institution. Minimum Requirements Bachelor's degree in Computer Science, Cybersecurity, Engineering, or a related field; or equivalent combination of education and experience. At least three years of experience in security engineering, AI/ML infrastructure, identity and access management, or systems administration. Experience with API gateway architectures and AI/LLM routing infrastructure (e.g., LiteLLM, Kong). Expertise in federated identity technologies including SAML2, OAuth 2.1, and OIDC. Experience with endpoint security platforms and data loss prevention tools. Knowledge of AI-specific threats such as prompt injection, jailbreak techniques, and agent drift. Linux system administration experience. Strong written and verbal communication skills. Preferred Qualifications Experience with AI detection and response platforms. Experience with Model Context Protocol (MCP) architectures and tool governance. Experience conducting threat modeling and adversarial testing of AI-enabled applications. Python scripting experience for security automation. Experience with SIEM platforms and security analytics. Familiarity with OWASP Generative AI security frameworks. Security, cloud, or AI-related certifications. Position Type Full-time position, hybrid flexibility. Must be available for 1-2 meetings per week in Durham, NC. Be Bold. Essential Job Duties Deploy and maintain AI gateway infrastructure in on-premise and cloud environments. Integrate AI detection, response, and compliance tooling. Conduct security reviews of AI-enabled applications. Develop and enforce AI security policies and governance controls. Monitor AI usage and telemetry to detect anomalous behavior. Coordinate adversarial and penetration testing exercises. Support procurement evaluation of AI security products. Design endpoint-level security controls for AI clients. Maintain dashboards and reporting to communicate AI security posture. Choose Duke. Why Work at Duke? Duke University offers the opportunity to work at the forefront of secure AI adoption within a leading research institution. You will help shape how AI technologies are safely deployed across teaching, research, and administration, while collaborating with experts across IT, compliance, and academic units. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.