2026 Summer Intern - Clinical Pharmacology

2026 Summer Intern - Clinical Pharmacology

Department Summary

Clinical Pharmacology is a dynamic function that plays a critical role in supporting drug development teams and in optimizing the dosing regimen for patients. Utilizing our expertise in pharmacokinetics and pharmacodynamics, Clinical Pharmacologists contribute at every stage of development, applying quantitative pharmacology principles across a molecule's life-cycle for both small molecules, biologics, and novel treatment modalities. The Clinical Pharmacology department is instrumental in shaping future treatments and ensuring they are both safe and effective.

This internship position is located in South San Francisco, CA, on-site.

The Opportunity

The key responsibilities may include, but are not limited to:

• Data Integration: Clean and curate longitudinal Phase III COPD data, including daily patient diaries (symptoms/rescue med use), frequent spirometry (FEV1), and inflammatory biomarkers.

• Model Development: Develop and implement Repeated Time-to-Event (RTTE) models to describe the frequency and timing of COPD exacerbations.

• Dynamic Predictor Analysis: Evaluate the impact of time-varying covariates (e.g., weekly symptom changes) vs. baseline characteristics in predicting the "hazard" of an event.

• Simulation: Conduct "Virtual Patient" simulations to quantify how different treatment effects impact the cumulative risk of exacerbations over a 52-week period.

• Strategic Insight: Communicate findings to cross-functional teams (Clinical Science, Biostatistics) to help refine future trial designs and patient selection criteria.

Program Highlights

• Intensive 12-weeks full-time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer)

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education: You meet one of the following criteria:

• Must be pursuing a PhD (enrolled student).

Required Majors: PhD program in Pharmacometrics, Biostatistics, Pharmaceutical Sciences, Biomedical Engineering, or a related quantitative field.

Required Skills:

• Hands-on experience with modeling and simulation, specifically with RTTE models.

• Familiarity with survival analyses and longitudinal data structures.

• Proficiency in R or Python.

Preferred Knowledge, Skills, and Qualifications

• Knowledge of NONMEM or Monolix can be a plus.

• Previous disease modeling experience in respiratory diseases (COPD/Asthma) is a plus.

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $50.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.