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Remote New

Principal Key Accounts Manager, Market Access

Exact Sciences
paid time off
United States
Jan 21, 2026

Help us change lives

At Exact Sciences, we're helpingchange how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others.

Position Overview

This role drives medical policy coverage initiatives, contracting strategies and payer utilization programs within assigned national, regional and local payers.This role supports Market Access strategy and implementation on a national level, including new markets. This role liaises with revenue cycle management and legal, and makes recommendations on billing, fee schedule maintenance and payer strategy. This role calls on payer organizations that impact reimbursement nationally, selling products within payer quality and other utilization programs, develops coverage policy for new products, provides technical and administrative product information and responds to requests for proposals.

This position is field based.

Essential Duties

Include, but are not limited to, the following:

  • Leads complex negotiations with national and regional payers, ensuring alignment with organizational goals and maximizing contract value.
  • Cultivates and expands long-term partnerships with existing insurance providers to enhance collaboration and contract performance.
  • Promotes diagnostic solutions within payer quality initiatives and utilization management programs to secure product inclusion and support adoption.
  • Acts as a Market Access advisor to field leadership, shaping regional strategies and guiding execution to exceed commercial targets.
  • Negotiates optimal reimbursement rates and terms to ensure financial sustainability and market competitiveness of diagnostic offerings.
  • Establishes and maintains detailed records of payer interactions, tracking progress and outcomes to inform future engagement strategies.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company's Quality Management System policies and procedures.
  • Maintain regular and reliable attendance.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day.
  • Ability to travel 50% of working time away from work location, may include overnight/weekend travel.

Minimum Qualifications

  • Bachelor's Degree in a field related to essential duties; or associate's degree and 2 years of relevant experience.; or High School Diploma or General Education Degree (GED) and 4 years of relevant experience.
  • 10+ years of experience in any of the following areas: Contracting and coverage with large payers, medical group contracting, sales, or sales leadership.
  • Demonstrated ability to perform the essential duties of the position with or without accommodation.
  • Applicants must be currently authorized to work in country where work will be performed on a full or part-time basis. We are unable to sponsor or take over sponsorship of employment visas at this time.

Preferred Qualifications

  • Demonstrated track record of developing and managing complex negotiations with multiple decision makers.
  • Ability to develop a value proposition and effective business case that will influence medical policy.
  • Ability to present clinical data, scientific findings, and complex information in a persuasive manner to a variety of audiences.
  • Existing relationships with individuals at insurance companies and group payer organizations.
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Salary Range:

$182,000.00 - $274,000.00

The annual base salary shown is a national range for this position on a full-time basis and may differ by hiring location. In addition, this position is bonus eligible.

Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.

Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.

Not ready to apply? Join our Talent Community to stay updated on the latest news and opportunities at Exact Sciences.

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.

To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub. The documents summarize important details of the law and provide key points that you have a right to know.

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