Levine Lab - Electrophysiologist (Assistant Professional Researcher)

Levine Lab - Electrophysiologist (Assistant Professional Researcher)

Department of Oral and Maxillofacial Surgery

University of California, San Francisco

The Levine Lab is seeking a skilled and motivated Electrophysiologist. Applications are being accepted for the position of Assistant Professional Researcher.

Key responsibilities:

• Ion Channel Biophysics: Conduct electrophysiological experiments using patch-clamp techniques to investigate ion channel properties and gating mechanisms in sensory neurons.
• Calcium Imaging: Use calcium imaging techniques (e.g., Fura-2, Fluo-4, GCaMP) to study intracellular calcium dynamics nociceptors.
• Neurophysiology: Investigate the role of ion channels in pain sensation and neural signaling by examining neuronal responses to pharmacological agents and mechanical, thermal, and chemical nociceptive stimuli.
• Human Sensory Neurons: Utilize primary human sensory neurons to study specific ion channel function.
• Data Analysis: Analyze large datasets from electrophysiology, imaging, and molecular experiments using appropriate software (e.g., MATLAB, Clampfit, ImageJ).
• Collaboration: Work alongside cross-disciplinary teams, including pharmacologists, molecular biologists, and computational biologists, to achieve research objectives.
• Documentation & Reporting: Prepare research reports, manuscripts for publication, and contribute to grant writing and lab compliance (e.g., IACUC, biohazard, BUA).

Required Qualifications:

• Doctorate in Physiology, Neuroscience, Biophysics, or a related field, plus 3+ years of relevant experience.
• Proficient in electrophysiology techniques (e.g., patch-clamp) and calcium imaging (e.g., Fura-2, GCaMP).
• Strong understanding of ion channel function and neuronal signaling pathways, especially in nociceptors.
• Data Analysis: Familiarity with tools such as MATLAB, Python, Clampfit, and ImageJ.
• Excellent written and verbal communication skills for preparing research reports and publications and institutional compliance.

Preferred qualifications:

• Advanced expertise in ion channel biophysics and electrophysiology.
• Experience working with rodent model and human primary sensory neurons, in vitro.
• Familiarity with calcium channels and their role in neuronal function is highly desirable but not required.
• Strong publication record in relevant fields (e.g., ion channel function in human and rodent nociceptors).
• Experience with managing projects and timeline, proactively identify potential research issues and troubleshooting.
• Able to train junior associates and productively manage project progress.
• Ability to work independently and as a member of a research team.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Willingness and ability to learn new methods and skills for changing research priorities.

See Table 13B for the salary range for this position. A reasonable estimate for this position is $93,400-$122,100.

Please apply online at: https://aprecruit.ucsf.edu/JPF05913 with a cover letter, CV, and contact information for two references. Applicant materials must list current qualifications upon submission.

• 2 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy

* UC Anti-Discrimination Policy

* APM - 035: Affirmative Action and Nondiscrimination in Employment