Research Professional 1-Genetics/Cell Bio

The Dehm Lab at the Masonic Cancer Center, University of Minnesota is investigating new therapies for treatment of men with advanced prostate cancer. We seek a highly motivated, detail-oriented Researcher with a strong background in mouse genetics and molecular/cell biology to independently manage critical in vivo and in vitro research components. This role requires exceptional organizational skills, rigorous preparation and adherence to protocols, and a commitment to meticulous, timely documentation.

50% - In Vivo Mouse Model Management: Maintain and track colonies of genetically-modified mice. Includes breeding, weaning, genotyping, and precise phenotyping. Perform detailed necropsies of the genitourinary (GU) tract and other tissues for downstream analysis.

35% - Advanced Cell and Molecular Biology: Establish and maintain organoid cultures from mouse tumor tissues. Perform a range of downstream assays including western blot, RT-PCR, colony formation, and drug treatments on both established prostate cancer cell lines and novel organoid models. Ensure experimental reproducibility.

10% - Data Analysis and Communication: Meticulously record, analyze, and interpret all data in a detailed, reproducible lab notebook. Prepare written reports, figures, and oral presentations to clearly communicate research approaches and outcomes to the Principal Investigator (PI) and collaborators.

5% - Lab Operations & Compliance: Proactively contribute to overall lab organization and maintenance (e.g., reagent stock, equipment logs, regulatory binder upkeep). Ensure strict compliance with all lab safety and scheduling policies.

All required qualifications must be included in the application materials

Required Qualifications:
-BA/BS in Biochemistry, Biology, Molecular Biology, or a related field or a combination of related education and work experience equal to 4 years.
-Essential technical skills include expertise in mouse colony management and maintenance (breeding, genotyping, phenotyping), and proficiency in sterile mammalian cell culture, western blotting, and PCR.

Preferred Qualifications:
-Experience in establishing and maintaining organoid or 3D cell cultures, specific experience with mouse necropsy and tissue harvesting/processing of the GU tract, and expertise with advanced molecular techniques such as chromatin immunoprecipitation (ChIP).

-Required professional competencies include accountability, organization, documentation, and communication.

The Masonic Cancer Center (MCC) is an NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting-edge research opportunities; and outstanding advanced education.

Pay Range: $42,000 - $45,000; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type: Civil-Service & Non-Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).