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Principal Medical Director, Neurodegeneration

Genentech
United States, California, South San Francisco
May 24, 2025
The Position

The Opportunity

We are seeking a dynamic medical leader with a background in Aging and Dementia/Behavioral Neurology to join the Medical network at Genentech. This position will report to the Therapeutic Area Lead (TAL) for Neurodegeneration within the Neurology Therapeutic Area. The Principal Medical Director will provide exceptional clinical and scientific leadership for medical affairs activities in the area of Alzheimer Disease and related disorders, aiming to generate and communicate medical evidence that aids practitioners, patients, and payers in making informed health care decisions. The successful candidate will exhibit outstanding communication and leadership skills, building strong relationships with key stakeholders. This role also requires representing the US Medical function within cross-functional teams and initiatives at Genentech, Roche's global organization, and external customer engagements, with an emphasis on leading fit-for-purpose teams, prioritizing work flexibly, and engaging in partnerships to address complex multidisciplinary challenges.

Key Responsibilities

  • Provide the medical perspective to a broader network of Medical Affairs professionals in both home and field organizations.

  • Contribute to defining science and medical strategies that lead to impactful medical affairs tactics, particularly in the early stages of asset and indication development.

  • Design, execute, and monitor medical strategies, plans, and tactics throughout the product lifecycle.

  • Represent Genentech Medical Affairs externally at key meetings.

  • Develop scientific partnerships with therapeutic area experts and execute collaborations.

  • Lead efficient implementation of medical tactics by leveraging relevant expertise and insights.

  • Execute US Medical/global clinical trial activities conducted as part of Medical Affairs.

Who you are

Required Qualifications & Experience

  • Board Certified physician with clinical experience in Aging and Dementia/Behavioral Neurology

  • Minimum 8+ years of relevant clinical / medical pharmaceutical/biotechnology industry experience with deep knowledge of Alzheimer Disease and related dementias

  • Experience or relevant knowledge of pre-approval drug development trials and/or post marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations

  • Understanding of the US health care environment including the payer landscape, evidence based medicine tools and practices, and health technology assessments

  • Ability to navigate complex and challenging situations and flex and thrive in an ambiguous environment.

Location/ Travel Requirements

The position is preferred to be located in South San Francisco but the candidate may be remote and would be required to spend time in the home office. The position may require up to an additional 35% time traveling.

The expected salary range for this position based on the primary location of South San Francisco, CA is $277,800 - 515,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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